Beneficial Health Potential of Algerian Polysaccharides Extracted from Plantago ciliata Desf. (Septentrional Sahara) Leaves and Seeds

Today, an ethnobotanical approach makes sense for identifying new active bioactive chemicals from uses of indigenous plants. Two water-soluble enriched polysaccharide fractions (L-PSPN and S-PSPN) were extracted by hot water extraction the leaves seeds Plantago ciliata Desf. (1798), a Mzab herb currently used in Algeria traditional healers. Primary investigation was performed describing main structural features these polysaccharides (pectin- heteroxylan-like compositions) using colorimetric assays, FTIR spectroscopy, HPAEC/PAD GC/MS-EI analyses. Some biological activities also monitored, such as anticomplement, anti-inflammatory (phagocytic ability, NOX2 MPO inhibitions) anti-diabetic (α-amylase α-glucosidase inhibitions). L-PSPC seems able to moderately modulate innate immune system (IC50 around 100 µg/mL) contribute wound-healing processes close 217 vs. 443 µg/mL sodium heparin). S-PSPC shows some potential anti-hyperglycemic 4.7 mg/mL) ranging 111 203 agent, well other (fiber) psyllium-like species.